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Updated: Sep 12, 2025

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在Syk上Y317的酸化负面调节ITAM和hemITAM介导的信号和血小板中的功能

Manal Elzoheiry1, Carol A Dangelmaier2, Dhruv N Vajipayajula1

  • 1Temple University School of Medicine, Philadelphia, Pennsylvania, United States.

Blood advances
|August 8, 2025
PubMed
概括

氨酸317在脏中的氨酸激酶 (Syk) 对血小板信号进行负面调节. 缺乏这种Syk酸化部位的小鼠表现出增强的血小板反应和更快的血块形成,揭示了它在血液细胞功能中的关键作用.

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