感知压力和全静电负荷:来自我们所有人的研究计划的结果
Faith Morley1, Lauren Mount1,2, Anjile An1
1Department of Population Health Sciences, Weill Cornell Medicine, New York, New York, United States of America.
PloS one
|August 8, 2025
概括
高压力加速生物衰老,增加慢性疾病的风险. 这项研究发现,感知到的压力显著提高了高全静电负荷 (AL) 的几率,即使考虑到健康的社会决定因素.
科学领域:
- 公共卫生 公共卫生
- 老年学是一门学科.
- 社会流行病学 社会流行病学
背景情况:
- 压力水平的上升带来了重大的公共卫生挑战.
- 压力与加速生物衰老和增加慢性疾病风险有关.
研究的目的:
- 调查感知压力与高静态负荷 (AL) 之间的关联.
- 探索社会背景因素对压力-AL关系的影响.
主要方法:
- 来自我们所有人研究计划 (2017-2022) 的7,415名参与者 (年龄18-65岁) 的横截面研究.
- 后勤回归分析以评估感知压力 (感知压力量表) 与高AL之间的关联.
- 对社会人口统计学因素和健康的社会决定因素 (歧视,孤独,粮食不安全,邻里混乱,社会凝聚力) 进行控制.
主要成果:
- 高压力在年轻人,接受医疗补助和西班牙裔参与者中普遍存在.
- 高压力与高AL的几率增加有显著的关联 (OR=2.18),这种关联在调整社会决定因素后仍然存在 (OR=1.29).
- 高压力和高AL之间的关联在贫困与收入比率中位数以上的个体中更为明显.
结论:
- 感知到的压力是过早生物衰老的重要预测因素,如高静态负荷所示.
- 解决健康的上游社会决定因素对于减轻压力的不良健康影响至关重要,特别是在边缘化社区.
- 针对减轻压力的干预措施可以帮助预防与加速生物衰老相关的慢性疾病.
更多相关视频
10:45A Community-based Stress Management Program: Using Wearable Devices to Assess Whole Body Physiological Responses in Non-laboratory Settings
Published on: January 22, 2018
7.7K
05:33Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature
Published on: June 19, 2019
8.6K
相关概念视频
Introduction to Stress and Lifestyle
177
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
177
Physiological Foundation of Stress
158
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
Role of the Sympathetic Nervous System
Adrenaline triggers the...
158
Psychological Responses to Stress
100
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
100
Hypothalamic-Pituitary Axis
61.7K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
61.7K
Stress Response System
199
The stress response system, also known as the fight-or-flight response, is the body's automatic physiological reaction to perceived threats. Hans Selye introduced the concept of General Adaptation Syndrome (GAS) to describe the predictable pattern of changes that occur in response to stress. GAS consists of three sequential stages: alarm, resistance, and exhaustion. This model helps explain how chronic stress can contribute to health problems.
Alarm stage
In the alarm stage, the body's...
Alarm stage
In the alarm stage, the body's...
199
Components of Stress
276
Stress analysis under multiple loading conditions is intricate, necessitating a comprehensive grasp of normal and shearing stresses. Consider a small cube at point O, subjected to stress on all six faces, visible or not. Normal stress components σx, σy, σz act perpendicularly to the x, y, and z axes. Shearing stress components τxy and τxz are exerted on faces perpendicular to these axes.
Interestingly, the hidden cube faces also experience these stresses, equal and...
Interestingly, the hidden cube faces also experience these stresses, equal and...
276
