MS/MS.

Keaton L Mertz1, Lia R Serrano1, Pavel Sinitcyn2

  • 1Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.

概括

这项研究引入了一种新的数据独立采集质谱法,该方法可变化四极选择宽度,以改善前体离子识别. 这种技术通过解决同隔离的前体来增强蛋白质组分析,从而获得更准确的结果.

相关概念视频

Mass Analyzers: Common Types01:19

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The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
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Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

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The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
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Double Resonance Techniques: Overview01:12

Double Resonance Techniques: Overview

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Mass Spectrometers01:16

Mass Spectrometers

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