为阿片类药物使用障碍开发虚假智能手机应用程序:可接受性和适应性研究
Kierstyn S Gallegos1, Jennifer S Potter1,2, Van L King1,2
1Be Well Institute on Substance Use and Related Disorders, University of Texas Health Science Center at San Antonio, 5109 Medical Drive, San Antonio, TX, 78229, United States, 1 210 450 3760.
JMIR formative research
|August 8, 2025
概括
开发并测试了一款用于治疗阿片类药物使用障碍 (OUD) 的虚假应用程序. 该应用程序被证明是合适的对照,大多数参与者认为它是活跃的,并报告高满意度,验证其在临床试验中的使用.
科学领域:
- 数字治疗学数字治疗学
- 行为健康 行为健康
- 临床试验方法论 临床试验方法论
背景情况:
- 阿片类药物使用障碍 (OUD) 治疗面临的挑战是,尽管有基于证据的药物治疗,但患者退出治疗.
- 处方数字疗法有可能改善OUD治疗的坚持和保留.
- 在随机临床试验中使用虚假应用程序是一种创新的方法来评估真正的数字治疗疗效.
研究的目的:
- 开发和评估一个虚假的智能手机应用程序,用于控制阿片类药物使用障碍 (OUD) 治疗研究.
- 通过评估参与者的感知和缺乏临床效果来确定假装应用程序作为安慰剂对照的适用性.
主要方法:
- 一项为期4周的试验,涉及21名参与者,测试了OUD的虚假智能手机应用程序.
- 适用性标准包括参与者认为应用程序是活跃的,并且没有显示抑郁症或生活质量的临床改善.
- 数据收集涉及干预前后评估,用户满意度调查和半结构面试,分析质量.
主要成果:
- 假装应用程序符合适用性标准:95%的参与者认为这是一个积极的干预,没有观察到显著的临床改善.
- 报告了高用户满意度 (91%),定性主题包括感知价值,行为变化潜力和可用性.
- 参与者的参与显示了平均17.8次登录,其中71%的人达到每周3次登录的目标.
结论:
- 开发的假装应用程序适合在针对OUD的数字治疗方法的随机临床试验中作为对照条件使用.
- 这种经过验证的假装应用程序提高了临床试验的严格性,确保准确评估处方数字治疗疗效.
- 这些发现支持使用精心设计的虚假数字疗法来严格评估基于应用程序的新型干预措施.
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