巴罗反射灵敏度预测了头向上倾斜测试在怀疑血管综合症的患者中诱导了血栓失速
Vincenzo Russo1, Angelo Comune1, Erika Parente1
1Cardiology Unit, University of Campania "Luigi Vanvitelli" - Ospedale Monaldi, Naples, Italy.
The American journal of cardiology
|August 8, 2025
概括
患有血管 (VVS) 的患者表现出增强的巴罗反射灵敏度 (BRS). 较高的BRS预测了VVS患者的头部向上倾斜测试 (HUTT) 响应和缩的阳性反应,有助于对的评估.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统功能 自主神经系统功能
背景情况:
- 巴罗反射敏感性 (BRS) 损伤在血管 (VVS) 中被假设.
- 在VVS中了解BRS对于诊断和预测昏昏发作至关重要.
研究的目的:
- 在疑似VVS的患者中评估BRS,进行头向上倾斜测试 (HUTT).
- 确定BRS在预测VVS患者的HUTT反应和 asystole中的作用.
主要方法:
- 在224名VVS患者和20名对照中使用序列方法计算BRS.
- 执行了NTG增强的HUTT,并分析了静止和测试期间的BRS值.
- 利用ROC曲线分析和多变量分析来识别BRS预测HUTT结果的预测因素.
主要成果:
- 与对照组相比,VVS患者的基线BRS显著高于对照组 (7 ± 3.5对 4.4 ± 1.9 ms/mmHg; p = 0.0013).
- 阳性HUTT结果的患者比负结果的患者有更高的BRS (8.1 ± 3.7对比4.8 ± 2.1 ms/mmHg; p = 0.0001).
- 一个BRS切线> 6.95ms/mmHg独立预测的HUTT阳性;> 8.2ms/mmHg预测的HUTT诱导的缩,具有66.7%的灵敏度和82.1%的特异性.
结论:
- 与健康个体相比,VVS患者表现出增强的巴罗反射灵敏度.
- 在疑似VVS的患者中,BRS是积极的HUTT反应和 asystole的有价值的独立预测器.
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