预防性动脉瘤囊栓塞用于内内血管动脉瘤修复
Alexandra Sansosti1, Thomas F X O'Donnell1, Edvard Skripochnik2
1Division of Cardiac, Thoracic, and Vascular Surgery, New York-Presbyterian, Columbia University Irving Medical Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
Journal of vascular surgery
|August 8, 2025
概括
在内血管大动脉修复 (EVAR) 中使用的形状记忆聚合物 (SMP) 插头可促进动脉瘤囊血栓形成和回归. 一年后的随访显示,囊缩率很高,没有内脏泄漏或重新干预.
科学领域:
- 血管外科 血管外科
- 医疗器械技术 医疗器械技术
- 生物材料是一种生物材料.
背景情况:
- 动脉瘤囊的行为影响了血管内主动脉修复 (EVAR) 后的长期存活率和再干预率.
- 在EVAR期间对动脉瘤囊的积极管理越来越感兴趣.
- 形状记忆聚合物 (SMP) 插头为动脉瘤囊栓塞提供了一种新的方法.
研究的目的:
- 调查SMP插头在EVAR期间对动脉瘤囊栓塞的实用性.
- 评估SMP插头在促进囊性血栓形成和回归方面的安全性和有效性.
- 为了评估EVAR的短期结果,使用SMP插头进行预防性囊栓塞.
主要方法:
- 对从2022年2月到2024年1月使用SMP插头进行EVAR的患者进行了回顾性研究.
- 对安全结果的评估,包括意外栓塞和囊孔.
- 评估疗效结果:动脉瘤体积和直径的变化,内脏泄漏和使用放射学软件的重新干预.
主要成果:
- 分析了29名患者的1年随访数据.
- 没有观察到内脏泄漏,再干预或不良安全事件.
- 中位数动脉瘤体积显示了17%的回归,中位数直径在1年内减少了6mm.
- 67%的患者表现出超过10%的动脉瘤体积回归;55%的患者表现出直径回归.
结论:
- 使用SMP插头进行预防性动脉瘤囊栓塞是安全有效的,可诱导囊囊血栓形成和回归.
- 一年后的随访表明,囊回归率高,没有内脏泄漏,没有重新干预.
- 由于其生物降解性和缺乏CT工件,SMP插头是传统栓塞材料的有希望的替代品.
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