使用抗精神病药物的患者的心血管风险管理 - - 定性可行性研究
Karlijn Joëlle van den Brule-Barnhoorn1, Kirstine Marieke Jakobs2,3, Jan van Lieshout4
1Department of Primary and Community Care, Radboudumc, Nijmegen, Netherlands karlijn.vandenbrule-barnhoorn@radboudumc.nl.
BJGP open
|August 8, 2025
概括
对抗精神病患者实施TACTIC心血管风险计划需要进行调整. 一项可行性研究确定了患者的紧张和GP的工作负担是障碍,但以人为中心的方法是促进者,指导未来的随机对照试验.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 一般实践 一般实践
背景情况:
- 服用抗精神病药物的患者面临心血管疾病 (CVD) 风险升高.
- 一般实践中,对于这一群体缺乏强大的心血管疾病风险管理策略.
- 在TACTIC计划中,试行了一种多学科的方法来降低心脏病风险,并审查抗精神病药物的使用.
研究的目的:
- 确定实施TACTIC干预的障碍和促进者.
- 确定未来随机对照试验 (RCT) 所需的调整.
- 评估干预的有效性和可实施性.
主要方法:
- 在三家荷兰一般实践中进行的定性可行性研究.
- 半结构面试与8名患者和2个重点小组与11名医疗保健专业人员.
- 分析以规范化过程理论为指导,使用框架方法.
主要成果:
- 障碍包括患者紧张,多学科会议动态和GP工作量.
- 调解员涉及以人为中心的方法,明确的信息和可适应的角色.
- 建议包括精神病学家汇总报告,改善患者期望管理和精细的目标群体定义.
结论:
- 在大型RCT之前,对TACTIC干预的调整是必不可少的.
- 可行性研究对于提高试验有效性和有效性至关重要.
- 这项研究强调了在接受抗精神病药物治疗的患者中需要量身定制的风险管理.
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