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帕夫科斯 (PAVFCOS):开发了用于袋门和阴道抽的核心结果集
Lillian Reza1, Lara Bapir2, Nusrat Iqbal1
1Robin Phillips Fistula Research Unit, St Mark's Hospital, Imperial College London, London, UK.
开发了一个新的以患者为中心的核心结果集 (COS) 囊门和阴道 (PAVF). 这一由七个标准化结果组成的标准化结果集将改善对这种具有挑战性的疾病的临床研究报告.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 胃肠病学 胃肠病学
- 患者报告的结果
背景情况:
- 囊门和阴道抽 (PAVF) 在患者护理中提出了重大挑战.
- 在PAVF的干预研究中缺乏标准化的结果报告.
研究的目的:
- 为涉及PAVF患者的干预研究开发以患者为中心的核心结果集 (COS).
- 建立对评估PAVF治疗的最关键结果的共识.
主要方法:
- 方法遵循了有效性试验中核心结果措施 (COMET) 准则.
- 一项系统性审查和患者的定性访谈确定了最初的结果.
- 一个在线的Delphi练习与70个利益相关者,包括患者和临床医生,优先结果.
- 患者和临床医生的共识会议最终确定了核心结果.
主要成果:
- 创建了一个长长的99个结果列表,减少到46个,然后通过两个Delphi轮优先级.
- 选择了七个核心结果:全球节评估,疼痛,出院对生活质量的影响,状腺愈合 (临床/放射学),新的状腺/,需要救援干预,以及全球生活质量.
- 参与者包括患者 (45%),结肠直肠外科医生 (31%),胃肠科医生 (11%),放射科医生 (6%) 和口袋专家护士 (7%).
结论:
- 开发的PAVFCOS是第一个将对PAVF患者至关重要的结果纳入其中.
- 在干预研究中实施PAVFCOS将使PAVF的结果报告标准化.
- 这种标准化对于改善对这种复杂疾病的治疗方法的评估至关重要.
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