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Updated: Sep 12, 2025

Directed Differentiation of Induced Pluripotent Stem Cells towards T Lymphocytes
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在多发性硬化症中使用ocrelizumab治疗后,在保存IgA B细胞的同时,持久的B细胞损伤

Alexandra Garcia1, Stephane Rodriguez2,3, Emilie Dugast1

  • 1INSERM, Center for Research in Transplantation and Translational Immunology CR2TI, UMR 1064, CHU Nantes, Nantes Université, Nantes, France.

Annals of clinical and translational neurology
|August 8, 2025
PubMed
概括

在复发性复发性多发性硬化症 (RR-MS) 中使用ocrelizumab (OCR) 治疗会改变B细胞配置,增加调控性B细胞. 在停止OCR后,天真B细胞以炎症特征重新出现,由更具调节性的B细胞平衡.

关键词:
B 细胞 B 细胞 B 细胞在 IgA A 里面.这是一个反CD2020的方法.多发性硬化症多发性硬化症一个单细胞RNA测序.

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