早期的Locus Coeruleus noradrenergic轴突损失导致阿尔茨海默病的嗅觉功能障碍

Carolin Meyer1, Theresa Niedermeier1, Paul L C Feyen1,2

  • 1German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

Nature communications
|August 8, 2025
PubMed
概括

早期阿尔茨海默氏病 (AD) 涉及由于嗅球 (OB) 中的诺亚上腺素 (NA) 损失导致的嗅觉缺陷. 吞这些NA轴突的微质会导致这种情况,这表明早期AD诊断的嗅觉测试.

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