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Updated: Sep 12, 2025

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model
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A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

Published on: November 18, 2022

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ALOX5调节了血管光滑肌细胞的灭,以影响腹腔大动脉动脉瘤的形成

Luobo Wang1,2, Bing Wang3

  • 1Department of Vascular Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.

Scientific reports
|August 8, 2025
PubMed
概括

阿拉基酸5-氧化酶 (ALOX5) 通过通过NF-κB通路增强热致死,促进腹腔大动脉动脉瘤 (AAA) 的发展. 在小鼠模型中,抑制ALOX5降低了AAA严重性和炎症.

关键词:
在ALOX5中使用ALOX5腹腔大动脉动脉瘤 腹腔大动脉动脉瘤在 NF-κBB 中.热灭菌的发生.

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