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Updated: Sep 12, 2025

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MCP-1-CCR2-M2巨细胞轴有助于扩散大B细胞淋巴瘤的进展,并抑制抗瘤免疫反应

Zhao-Feng Wen1,2,3, Qi-Tang Huang1,2,4, Yang-Yang Wang1

  • 1Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, China.

Scientific reports
|August 8, 2025
PubMed
概括

用CCR2抗剂向MCP-1/CCR2轴有效地抑制扩散性大B细胞淋巴瘤 (DLBCL) 的进展,通过抑制原瘤的M2巨细胞极化和增强抗瘤T细胞反应.

关键词:
抗瘤免疫反应是一种免疫反应.扩散大的B细胞淋巴瘤.M2巨细胞的两极分化在MCP-1/CCR2轴上一个进步的进步.

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