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Updated: Sep 12, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

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开发一种多功能底盘,用于高效地生产各种II型多基化物

Yang Zou1,2, Ronghui Wang1, Zhengjie Liu2

  • 1Department of Urology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, Hubei Province, China.

Nature communications
|August 8, 2025
PubMed
概括

我们开发了Chassis2.0,一种修改后的Streptomyces宿主,用于高效地生产各种II型多基基菌 (T2PKs). 这种工程菌株过度生产抗生素,并使得新型化合物的发现成为可能.

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