在中年成人中,肌肉脂肪比率和骨密度之间的性别特定关联
Fang Jin1, Songting Gao2, Xiaocong Yao1
1Department of Osteoporosis Care and Control, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, 311200, Zhejiang, China.
Scientific reports
|August 9, 2025
概括
该研究发现,较高的骨肌肉质量与内脏脂肪组织面积比率 (SVR) 与中年男性更好的骨矿物质密度 (BMD) 有关. 绝经前妇女在特定的SVR范围内显示最佳的BMD.
科学领域:
- 老年学是一门学科.
- 骨健康 骨健康 骨健康
- 身体组成分析 身体成分分析
背景情况:
- 随着年龄的增长,骨质疏松症的风险会增加,特别是在中年人群中.
- 身体组成 (包括骨肥胖症) 与骨健康之间的相互作用尚未完全理解.
- 了解这些关系对于有针对性的健康干预至关重要.
研究的目的:
- 为了研究骨肌肉质量与内脏脂肪组织面积比率 (SVR) 和骨矿物质密度 (BMD) 之间的关联.
- 为了检查这种联系如何根据中年成人性别和更年期状况而有所不同.
- 通过身体组成管理,提供有关优化骨健康的见解.
主要方法:
- 来自国家健康和营养检查调查 (2011-2018) 的4349名中年成人 (40-59岁) 的数据分析.
- 使用双能X射线吸收计测量骨肌肉质量 (SMM),内脏脂肪组织面积 (VATA) 和腰部BMD.
- 应用多变量回归模型,对性别和更年期状态进行分层分析.
主要成果:
- 在肌量 (SMM) 和骨矿物质密度 (BMD) (β=12.8) 之间发现了正相关性.
- 内脏脂肪组织区域 (VATA) 与 BMD 的反向关系 (β=-0.5).
- 男人表现出SVR和BMD (β=342.4) 之间的积极关联;绝经前妇女显示出非线性,反转的U形关系,最佳SVR值为0.31kg/cm2.
结论:
- 骨肌肉质量与内脏脂肪组织面积比率 (SVR) 与中年成人腰部骨矿物质密度 (BMD) 有关.
- 存在显著的性别特异性差异:更高的SVR与男性更高的BMD相关.
- 绝经前妇女的骨质量在特定的SVR范围内得到优化,这表明了针对骨健康的量身定制方法.
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