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Updated: Jul 14, 2026

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
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Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

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对MUT-16支架蛋白相分离和客户端识别的多尺度模拟

Kumar Gaurav1, Virginia Busetto2, Diego Javier Páez-Moscoso3

  • 1Institute of Molecular Physiology, Johannes Gutenberg University Mainz, Mainz, Germany; Institute of Molecular Biology (IMB), Mainz, Germany; KOMET1, Institute of Physics, Johannes Gutenberg University Mainz, Mainz, Germany.

Biophysical journal
|August 9, 2025
PubMed
概括

蛋白质相分离是细胞组织的关键. 这项研究揭示了MUT-16蛋白质凝聚物如何招募MUT-8,这对于C. elegans中RNA沉默至关重要,使用多级模拟和实验.

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相关概念视频

Assembly of Signaling Complexes01:30

Assembly of Signaling Complexes

Multiprotein signaling complexes are formed in a dynamic process involving protein-protein interactions at the cytoplasmic domain of transmembrane receptors or enzymatic and non-enzymatic proteins associated with the receptor. These complexes ensure the activation and propagation of intracellular signals that regulate cell functions.
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...