商用植物固醇产品的标签有多可靠? 一个为期12周的随机双盲训练研究
Joshua Dissemond1, Tim Havers1,2, Steffen Held3
1IST University of Applied Sciences, Department of Fitness and Health, Duesseldorf, Germany.
Journal of the International Society of Sports Nutrition
|August 9, 2025
概括
这项研究发现,结合20-基 (20E) 和迪奥斯基宁 (DSG) 的补充剂并没有提高男性的抵抗训练结果. 该补充剂的含量远低于声称的20E和DSG,因此没有可衡量的益处.
科学领域:
- 运动生理学 运动生理学
- 营养生物化学 营养生物化学
- 药理学 药理学是指药理学的学科.
背景情况:
- 像20-hydroxyecdysone (20E) 和diosgenin (DSG) 这样的植物类药物表现出潜在的合成体效应.
- 在补充剂中,结合植物固醇是常见的,先前的研究表明添加剂效应.
- 关于20E和DSG联合作用的人类研究有限.
研究的目的:
- 评估商业上可用的20E和DSG补充剂在抵抗训练的男性中具有的合成代谢和提高性能的潜力.
- 评估补充剂对力量,身体组成和肌肉厚度的影响.
- 分析补充剂中20E和DSG的实际度和生物活性.
主要方法:
- 28名经过抵抗训练的男性被随机分配到20E/DSG补充剂组或安慰剂组12周.
- 参与者接受了标准化的自由重量阻力训练计划.
- 测量包括1-RM强度,体重,身体组成,肌肉厚度和血液标志物;补充分析和体外试验也进行了.
主要成果:
- 两组在12周内都显示出强度和身体组成的显著改善,补充剂和安慰剂组之间没有显著差异.
- 分析显示,补充剂含有不到1%的声称20E和10.4%的声称DSG.
- 在用补充剂治疗的C2C12细胞中,没有观察到生物活性或增殖效应.
结论:
- 测试的植物类固醇补充剂没有提供除了抵抗训练之外的额外的合成代谢或性能益处.
- 补充剂中20E和DSG的低度和缺乏生物活性可能解释了缺乏群体特异性的影响.
- 未来的植物固醇研究应该优先验证化合物度,纯度和生物活性,以确保可靠的发现.
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