局部素应用对肌肉代谢反射和微血管反应能力的影响
Nikolaus D Carpenter1, Aaron E Wahl1, Alec L E Butenas2
1Exercise and Sport Science Department, La Crosse, Wisconsin, USA.
Physiological reports
|August 9, 2025
概括
在男性或女性的运动后循环停止 (PECA) 期间,局部素没有显著改变血压. 然而,它增强了炼手臂的微血管反应能力,表明局部血管效益.
科学领域:
- 运动生理学 运动生理学
- 心血管监管 监管心血管系统
- 血管生物学 血管生物学
背景情况:
- 在男性中已知局部素对运动压力反射的影响,但其对女性和微血管功能的影响尚不清楚.
- 代谢反射是运动期间心血管控制的关键机制,受各种因素的影响,包括局部药物.
研究的目的:
- 在健康的男性和女性中研究局部素在运动后循环停止 (PECA) 期间对血压的影响.
- 为了确定局部素是否增强了任何性别的微血管反应能力.
- 为了探索在模拟的运动停止期间对局部素的潜在性别特异性反应.
主要方法:
- 健康的男性和女性被分配给运动臂,非运动臂或对照条件施加素.
- 在手握运动和随后的PECA期间测量血压.
- 在封闭后反应性高血压期间,使用近红外光谱 (NIRS) 评估了微血管反应性.
主要成果:
- 在两性中,局部素在PECA期间没有显著改变血压 (p > 0.05).
- 显著的相互作用显示,在草素应用后,炼手臂的微血管反应增强 (p = 0.01).
- 没有观察到代谢反射诱导的血压变化的显著减弱.
结论:
- 在PECA期间,局部素似乎没有减弱代谢反射诱导的血压反应.
- 素通过增强受治疗的肢体中的微血管反应能力来证明局部血管的益处.
- 需要进一步的研究来阐明潜在的性别差异对局部素及其血管效应的反应.
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