成功减少坐着的时间可以提高代谢灵活性.
Taru Garthwaite1, Tanja Sjöros1, Saara Laine1
1Turku PET Centre, University of Turku, Turku University Hospital, and Åbo Akademi University, Turku, Finland.
Scandinavian journal of medicine & science in sports
|August 9, 2025
概括
每天减少30分钟的坐时间可以改善代谢灵活性 (MetFlex) 和代谢综合征的成年人胰岛素敏感性. 这种干预有助于预防心脏代谢疾病.
科学领域:
- 代谢生理学 代谢生理学
- 心脏代谢健康状况
- 行为医学是一种行为医学.
背景情况:
- 久坐不动的行为和代谢灵活性受损 (MetFlex) 与心脏代谢疾病有关.
- 减少静坐时间和MetFlex之间的确切关系需要进一步阐明.
研究的目的:
- 为了研究降低代谢综合征的成年人每日静坐时间对MetFlex的影响.
- 为了确定旨在减少久坐行为的干预措施是否可以增强基质氧化和MetFlex.
主要方法:
- 64名具有代谢综合征的久坐不动的成年人被随机分配到干预 (INT) 或控制 (CON) 组6个月.
- INT组的目标是通过增加站立和非运动的体力活动,通过加速度计监测,减少每天1小时的静坐时间.
- 使用间接热量计和高胰岛素血糖-高血糖粘合剂评估了MetFlex,基质氧化和胰岛素敏感性.
主要成果:
- 干预组成功地减少了每天41分钟的静坐时间.
- 虽然整体MetFlex没有变化,但在最大运动期间的碳水化合物氧化在INT组中得到改善 (p=0.03).
- 每天减少≥30分钟的静坐时间的个体在低强度运动期间 (p<0.05) 显示胰岛素刺激的MetFlex和脂肪氧化得到改善.
结论:
- 成功地将每天的坐时间减少至少30分钟,可以提高代谢灵活性 (MetFlex) 和胰岛素敏感性.
- 这些改进表明,在高危人群中预防心脏代谢性疾病的潜在策略.
- 在MetFlex的变化与增加的站立时间和改善的胰岛素敏感性相关.
更多相关视频
09:19Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
Published on: February 2, 2019
10.0K
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
12.7K
相关概念视频
Metabolic States of the Body: The Postabsorptive State
544
The postabsorptive state usually starts about four hours after a meal and lasts until the next meal is eaten. During this time, the digestive system stops absorbing nutrients, and the body uses stored energy reserves to maintain stable blood glucose levels.
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
544
Regulation of Metabolism
9.9K
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
9.9K
Metabolic States of the Body: The Absorptive State
792
During the absorptive state, which lasts approximately four hours after a meal, the body absorbs nutrients from the gastrointestinal tract. The carbohydrates, proteins, and lipids we consume are broken down into monosaccharides, amino acids, and free fatty acids for absorption. While carbohydrates and proteins are absorbed as-is, lipids are absorbed in their broken-down forms and then re-esterified into triglycerides within enterocytes before being packaged into chylomicrons. These absorbed...
792
Other Glycolytic Pathways
215
The pentose phosphate pathway (PPP) operates in parallel with glycolysis, facilitating the metabolism of both pentoses and glucose. This pathway consists of two distinct phases: the oxidative and non-oxidative phases. While it does not directly generate ATP, the intermediates formed during the process can integrate into glycolysis, contributing to cellular energy metabolism when required.Oxidative Phase: NADPH ProductionThe oxidative phase of the pentose phosphate pathway is primarily...
215
Metabolic Rate
513
The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
513
Overview of Metabolism
31.9K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
31.9K
