慢性鼻炎的长期临床控制:手术后五年以上的结果
Gonneke E Joustra1,2, Marc C den Heijer3,4, Rahma Q H Al Yousef3
1Department of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. g.e.joustra@umcg.nl.
概括
慢性鼻炎 (CRS) 的内镜内鼻外科手术的长期结果显示,只有25%的患者能够完全控制症状. 过敏和喘等因素影响疾病控制,突出了需要多维治疗方法的需要.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏和免疫学 过敏和免疫学
- 生活质量研究 研究 生命质量研究
背景情况:
- 慢性鼻炎 (CRS) 是一种普遍存在的,具有重大社会经济影响的致残性疾病.
- 改善与健康相关的生活质量 (HRQoL) 和保持临床控制是CRS的主要治疗目标.
研究的目的:
- 评估CRS患者在五年内进行内镜内外科手术 (EES) 后的临床控制.
主要方法:
- 一项观察性队列研究包括123名CRS患者.
- 患者填写了内镜内鼻腔和头骨底部手术问卷,并更新了关于鼻炎和鼻 (EPOS) 标准的欧洲立场文件.
- 单变量分析确定了与临床对照结果相关的因素.
主要成果:
- 只有25.2%的CRS患者在EES后获得了"控制"的症状,而48.0%的患者"不受控制".
- 与较差控制相关的因素包括NSAID加剧的呼吸道疾病,过敏性鼻炎,修复手术,吸烟,喘和鼻.
- HRQoL的物理领域是最有影响力的,其次是社会和心理领域.
结论:
- 根据更新的EPOS标准,长期 (5年以上) 的EES对CRS导致只有25%的患者的症状得到控制.
- 确定影响疾病控制的因素对于提高治疗疗效至关重要.
- 考虑患者观点的多维方法对于管理CRS至关重要.
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