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通过与RNA聚合酶相互作用,17-hydroxy-jolkinolide B具有抗Mycobacterium结核病活性

Xiuyan Han1, Changming Chen2, Renxiang Zhao3

  • 1Pharmaceutical Research Center, Second Affiliated Hospital of Dalian Medical University, Dalian 116044, People's Republic of China.

Bioorganic chemistry
|August 9, 2025
PubMed
概括

来自Euphorbia fischeriana的一种新型化合物17-基基诺化B (HJKB),对结核病 (TB) 细菌表现出强烈的活性. HJKB抑制转录,并为结核病治疗提供一种潜在的天然产品.

关键词:
17-基基诺化物B 17基基诺化物B这种植物是Euphorbia fischeriana.在MDR/XDR-TB中使用.结核病菌菌菌的结核病菌的结核病菌.的RNA聚合酶.

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