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怀孕和哺乳期妇女在B组链球菌II期临床试验中的担忧:乌干达坎帕拉的一项定性研究
Agnes Ssali1, Phiona Nalubega2, Rita Namugumya2
1Medical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda; Makerere University -John Hopkins University Research Collaboration, Kampala, Uganda.
Vaccine
|August 9, 2025
概括
乌干达的母亲对疫苗的犹源于对副作用的恐惧,缺乏知识和社区的耻辱感. 让家庭和社区的利益相关者参与,对于理解和接受孕产妇免疫试验至关重要.
科学领域:
- 孕产妇和儿童的健康
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 新生儿感染构成重大威胁,特别是在低收入和中等收入国家.
- 孕产妇疫苗为减少新生儿感染提供了一个有希望的策略.
- 对于疫苗的犹是实施孕产妇免疫计划的一个主要障碍.
研究的目的:
- 探索乌干达怀孕和哺乳期妇女参与B组链球菌 (GBS) 临床试验中对疫苗犹的担忧和原因.
- 确定影响妇女在怀孕期间对母体疫苗接种决定的因素.
主要方法:
- 定性研究,采用与孕妇的深入采访和与哺乳妇女的焦点小组讨论.
- 参与者是年龄在18-39岁之间的女性,她们在乌干达参加了一项GBS临床试验.
- 用专题分析来分析收集的数据.
主要成果:
- 对疫苗潜在副作用的恐惧是所有犹不决的妇女的主要担忧.
- 缺乏关于孕产妇疫苗的知识,社区谣言,耻辱和研究程序都导致了犹.
- 对男性伴侣的看法以及对胎儿进行疫苗接种决策的责任的担忧也很重要.
结论:
- 解决孕产妇对疫苗的犹需要采取多方面的方法,解决对副作用和错误信息的恐惧.
- 让家庭,社区领袖和医疗保健工作者参与是提高对孕产妇免疫接种的理解和接受的必要条件.
- 成功实施孕产妇免疫试验需要社区和家庭的参与,以确保明智的决策.
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