补充养方法对婴儿营养状况的影响:一项随机临床试验
Cátia Regina Ficagna1, Elma Izze da Silva Magalhães1, Abby Branchini Chacón1
1Graduate Program in Food, Nutrition, and Health, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Nutrition (Burbank, Los Angeles County, Calif.)
|August 9, 2025
概括
不同的婴儿养方法会影响婴儿的生长. 婴儿主导的固体介绍 (BLISS) 与较低的BMI有关,而混合养减少了12个月以下婴儿超重风险.
科学领域:
- 儿科 儿科 儿科
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 补充养 (CF) 实践显著影响婴儿的成长和长期健康.
- 了解不同CF方法对人类测量结果的影响对于早期预防肥胖至关重要.
研究的目的:
- 评估三种补充养 (CF) 方法对9个月和12个月大的婴儿人体测量结果的影响:父母主导的断奶 (PLW),婴儿主导的固体介绍 (BLISS) 和混合方法.
主要方法:
- 一项随机临床试验,涉及巴西140对母婴.
- 参与者被随机分配到PLW,BLISS或混合CF方法,并提供标准化的指导.
- 婴儿的人类测量测量 (体重,长度) 和衍生的z-scores (体重为年龄,长度为年龄,体重为长度,BMI为年龄) 在9个月和12个月被评估.
主要成果:
- 与PLW组相比,BLISS组的婴儿在12个月内显示出较低的平均BMI-for-agez分数 (调整后的β: -0.53,P=0.035).
- 混合CF方法与9至12个月的超重/肥胖风险降低有关 (调整HR:0.11,P=0.048).
- 对于其他初级或二级的人类测量结果,没有发现显著的关联.
结论:
- 婴儿辅助辅助养方法,如BLISS和混合养,显示出可能带来有利的短期人类测量结果.
- 这些发现表明,婴儿指导方法在早期预防肥胖方面可能发挥作用,需要进一步调查.
- 需要对更大的队列进行长期研究,以确认这些CF方法对预防儿童肥胖的持续影响.
相关概念视频
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
304
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
304
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
420
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
420
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
284
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
284
Clinical Trials
8.3K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
8.3K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
174
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
174
Study Designs in Epidemiology
418
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
418


