酸化变异的表征用于识别Zea中的适应性等位基因
Qinjie Chu1, Tianxu Yang1, Xiaokang Quan2
1Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
The Plant journal : for cell and molecular biology
|August 9, 2025
概括
在玉米和茶中,酸化相关的单核酸变异 (pSNV) 揭示了适应性进化. 这些对于植物信号传递至关重要的psnv在野生亲属中显示出更强的选择性,为作物改进提供了洞察力.
科学领域:
- 植物基因组学 植物基因组学
- 进化生物学 进化生物学
- 分子信号传输的方法
背景情况:
- 在大规模基因组测序中,区分因果基因突变与中性变异是具有挑战性的.
- 酸化机械在植物发育和适应环境变化的过程中起着至关重要的作用.
- 了解像teosinte这样的野生亲属的遗传变异是改善玉米的关键.
研究的目的:
- 在Zea属中全面分析酸化相关的单核酸变异 (pSNVs).
- 了解PSNVs在teosinte和种植玉米之间的适应变异中的作用.
- 探索pSNVs在植物物种中的进化模式和功能影响.
主要方法:
- 基因组测序234个teosinte和507种种植玉米的加入.
- 针对酸化机械的单核酸变体的识别和分析.
- 对PSNVs,遗传保护,选择压力和基因表达的比较分析.
- 在玉米,Arabidopsis thaliana,大米和小麦中研究psnv的融合进化.
主要成果:
- 在Zea属中鉴定了33,687种psNV,其遗传保护减少,相关基因的蛋白质丰度/表达增加.
- pSNV比其他误解突变更强烈地经历了净化选择.
- 玉米的pSNV比theosinte少,这归因于选择和搭便车.
- pSNV与酶基质重写,进化分歧和像开花时间这样的特征有关.
- 在玉米和其他植物物种之间发现了46种融合进化的pSNV.
结论:
- pSNVs是Zea属适应性变异的重要驱动因素,特别影响开花时间.
- 野生teosinte港口拥有丰富的pSNV储备,具有提高作物的潜力.
- 将蛋白质信号位点纳入野生物种分析中,有助于发现适应性等位基因.
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