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中枢神经系统疾病中的肝X受体激动剂:从神经保护到临床挑战

Qian Zhang1, Jin-Dong Mao1, Min Wang2

  • 1Department of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, PR China; Department of Pharmacology, School of Pharmacy, Air Force Medical University, Xi'an, Shaanxi 710032, PR China.

Neuroscience
|August 9, 2025
PubMed
概括

肝X受体 (LXR) 激动剂通过减少神经炎症和促进神经生成,对中枢神经系统 (CNS) 疾病有前途. 然而,副作用需要优化LXR疗法才能有效的临床使用.

关键词:
中枢神经系统中枢神经系统脂质代谢 脂质代谢 是一种肝脏的X受体是一个X受体.神经新生是什么意思 神经新生是什么意思神经炎症是一种神经炎症.

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