相关实验视频
Updated: Sep 12, 2025

06:07
Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
6.8K
在吸烟者中,高咖啡消费可能会增加大动脉直径和腹部大动脉动脉瘤的风险
Joanna Kaluza1,2, Otto Stackelberg3,4, Martin Björck5
1Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 , Stockholm, Sweden. joanna.kaluza@ki.se.
Scientific reports
|August 9, 2025
概括
高咖啡消费可能会增加腹腔大动脉动脉瘤 (AAA) 和大动脉直径的风险,特别是在吸烟者中. 当与吸烟相结合时,这种风险会被放大,这表明对血管健康有协同效应.
科学领域:
- 心血管流行病学心血管流行病学
- 这是血管外科手术.
- 公共卫生 公共卫生
背景情况:
- 咖啡消费与腹腔大动脉瘤 (AAA) 风险之间的关系尚不清楚.
- 吸烟是已知的AAA风险因素,其与咖啡消费的相互作用需要调查.
研究的目的:
- 调查咖啡消费与AAA风险之间的关联.
- 检查吸烟状态在咖啡消费和AAA之间的关系中所起的改变作用.
- 评估咖啡消费对下内大动脉直径 (IAD) 的影响.
主要方法:
- 一项前性队列研究,涉及42,723名瑞典男性和34,921名女性 (年龄在45-83岁之间).
- 在8,109名男性中测量了下大动脉直径 (IAD).
- 18.7年的随访确定了1863例AAA病例,并评估了IAD测量.
主要成果:
- 与从未吸烟者相比,咖啡消费>5杯/天与非破裂AAA风险增加4倍和破裂AAA风险增加4.6倍有关.
- 在男性中,较高的咖啡消费量 (>3杯/天) 显著增加了IAD≥30mm的风险,特别是在目前的吸烟者中 (增加6.6倍).
- 观察到吸烟和咖啡消费与AAA风险之间存在显著的乘法相互作用 (P=0.009).
结论:
- 高咖啡消费可能会增加患腹腔大动脉动脉瘤 (AAA) 的风险.
- 咖啡消费似乎会增加下大动脉直径,特别是在吸烟者身上.
- 高咖啡摄入量和吸烟的联合效应对AAA的发展和进展构成重大风险.
相关概念视频
Stress Prevention and Stress Management Techniques IV
62
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
62
Coronary Artery Disease I: Introduction
55
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
55
Aneurysm II: Clinical Manifestations and Diagnostic Studies
23
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
23
Atherosclerosis III: Management
35
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
35
Coronary Artery Disease IV: Preventive Measures
32
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
32
Cancer Prevention
6.3K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.3K

