对比实施策略的有效性,以改善退伍军人的肝脏和结肠癌查:大型集群随机化实施研究的协议
Shari S Rogal1,2,3, Vera Yakovchenko4, Timothy R Morgan5,6,7
1Center for Healthcare Evaluation, Research, and Promotion, VA Pittsburgh Healthcare System, PA, Pittsburgh, USA. rogalss@upmc.edu.
Implementation science : IS
|August 9, 2025
概括
这项研究比较了患者导航和外部便利,以改善退伍军人的胃肠癌查. 这些发现将为结直肠癌和肝细胞癌查完成的策略提供信息.
科学领域:
- 实施科学 实施科学
- 医疗服务研究 医疗服务研究
- 癌症查差异的差异
背景情况:
- 胃肠道癌症查,包括结肠直肠癌 (CRC) 和肝细胞癌 (HCC),面临不充分和不公平的实施,造成可预防的伤害.
- 本研究方案概述了外部便利与患者导航的比较,以提高退伍军人卫生管理局 (VA) 内的癌症查完成率.
研究的目的:
- 为了比较患者导航与外部便利化的有效性,提高退伍军人中HCC和CRC查完成率.
- 评估影响各种退伍军人群体查完成的实施决定因素,前提条件和调节者.
主要方法:
- 将进行两项混合型3型,集群随机试验,根据初级保健地点随机分配退伍军人.
- 该HCC试验将包括24个地点,CRC试验将包括32个地点.
- 主要结果是查完成范围,评估干预后和维持期间,使用CFIR映射的调查和采访.
主要成果:
- 主要结果是癌症查完成的程度,在干预后和维持阶段进行测量.
- 将使用混合方法 (调查和采访) 评估实施决定因素,先决条件和主持者.
结论:
- 将这两项试验进行比较,将揭示一次性CRC查与医疗复杂患者中重复性HCC查的实施策略如何不同.
- 这项研究旨在优化胃肠道癌查,减少VA系统内的差异.
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