在住院患者中推药物订单中的药物错误的流行率和类型:一个横截面研究
Arefeh Rasouli-Rad1, Mahdi Ahmadinia2, Azadeh Eshraghi1
1Department of Clinical Pharmacy and Pharmacoeconomics, School of Pharmacy, Iran University of Medical Sciences, Tehran, Iran.
Journal of pharmaceutical health care and sciences
|August 9, 2025
概括
在医院中,由于文档不足,Pro Re Nata (PRN) 药物错误很常见. 改善电子处方和医疗教育对于患者安全至关重要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 患者安全 患者安全
- 医院管理局 医院管理局
背景情况:
- 在医院中,Pro Re Nata (PRN) 处方经常与药物错误有关.
- 缺乏PRN订单的文档有助于增加药物不良事件的风险.
- 现有的患者安全倡议还没有充分解决PRN处方做法.
研究的目的:
- 确定住院患者中PRN药物错误的患病率和类型.
- 识别导致错误的高风险PRN药物.
- 探索与PRN处方错误相关的因素.
主要方法:
- 在2023年进行了一项涉及400名接受PRN处方的住院患者的横截面研究.
- 数据采集使用基于临床指导方针和专家输入的标准化表格.
- 统计分析包括千平方测试和后勤回归来确定错误趋势和风险因素.
主要成果:
- 74.1%的PRN处方缺乏文档说明,91.1%的处方间隔被遗漏.
- 佩提丁是最常被处方的PRN药物 (32.6%).
- 手术ICU的错误率更高;缺少剂量间隔和高依赖病房的入院是错误的关键预测因素.
结论:
- 高率的PRN处方错误需要改进文档和有针对性的医疗保健专业人员培训.
- 实施电子处方和专注医疗教育等结构化干预措施可以显著减少错误.
- 监管执法与教育倡议一起,对于提高PRN药物管理中的患者安全至关重要.
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