相关实验视频

Updated: Sep 12, 2025

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

可见的膜收缩是早期非小细胞肺癌的预后标志物:一项回顾性队列研究

Yikai Xing¹, Jian Zhou¹, Zhenyu Yang¹

¹Department of Thoracic Surgery and Institute of Thoracic Oncology, West China Hospital, Sichuan University, Guoxue Alley, Chengdu, China.

Annals of surgical oncology

|August 9, 2025

概括

可见膜收缩 (VPR) 是小瘤非小细胞肺癌 (NSCLC) 患者预后不良的可靠指标. 这一发现为手术决策提供了实时指导,独立于内脏膜入侵 (VPI) 状态.

科学领域:

胸部瘤学胸部瘤学
手术瘤学手术瘤学
癌症预后癌症预后

背景情况:

内脏膜入侵 (VPI) 是非小细胞肺癌 (NSCLC) 的关键预后因素,影响手术方法.
及时确认VPI具有挑战性,需要使用替代的预后标志物.
可见膜收缩 (VPR) 假设与VPI相关,并提供类似的预后价值.

研究的目的:

评估在NSCLC患者中可见膜收缩 (VPR) 的预后意义.
确定VPR是否可以为手术决策提供实时指导.
评估VPR的预后价值与内脏膜入侵 (VPI) 状态的独立性.

主要方法:

对2033名瘤直径≤2厘米的NSCLC患者进行了回顾性队列研究,这些患者接受了彻底手术.
根据VPI和VPR状态进行了生存分析 (无复发生存[RFS]和整体生存[OS]).
多变量考克斯回归确定了独立的预后因素.

主要成果:

与没有VPR的患者相比,VPR患者的RFS和OS显著恶化 (HR分别为4.91和7.44).
在患有VPR的患者中,根据VPI状态 (HR ~1) 没有观察到RFS或OS的显著差异.
多变量分析证实,VPR是不良RFS和OS的独立风险因素 (HR分别为6.57和8.817).

结论:

可见膜收缩 (VPR) 作为一个可靠和及时的预后标记在T≤2cmN0M0 NSCLC.
VPR的预后值独立于内脏膜入侵 (VPI) 状态.
VPR可以帮助NSCLC患者实时进行手术决策.

关键词:

非小细胞肺癌是非小细胞肺癌.预测预后预测预测追溯性队列研究追溯性队列研究腹腔内脏侵袭腹腔内脏侵袭可见的多叶膜收缩.

更多相关视频

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

Prone Lateral Minimally Invasive Retropleural Corpectomy Using a Rotatable Radiolucent Jackson Table

Prone Lateral Minimally Invasive Retropleural Corpectomy Using a Rotatable Radiolucent Jackson Table

Published on: July 3, 2025

相关概念视频

Pneumothorax-II

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

Pleural Effusion I: Introduction

Pleural Effusion I: Introduction

Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...