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mRNA主要增强疫苗接种促进了生殖中心反应中的克隆连续性,并扩大了SARS-CoV-2变种覆盖范围

Matias Ciancaglini1, Jonas Fixemer1, Cemre Seven1

  • 1Department of Biomedicine, University of Basel, Petersplatz 10, 4051 Basel, Switzerland.

Molecular therapy : the journal of the American Society of Gene Therapy
|August 10, 2025
PubMed
概括

与腺病毒/mRNA相比,mRNA/mRNA接种促进了持久的B细胞反应和更广泛的抗体保护对抗SARS-CoV-2变体. 高B细胞克隆连续性是针对不断演变的病原体的有效疫苗的关键.

关键词:
这就是SARS-CoV-2病毒.腺病毒载体病毒载体.克隆性选择 克隆性选择发芽中心是生殖中心.在mRNA疫苗的使用中.中和抗体中和抗体.主要增强免疫接种的免疫.接种疫苗 接种疫苗变体覆盖范围的变体覆盖范围

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