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Updated: Sep 8, 2025

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I
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[非阻塞性阿佐精子症的免疫机制:基于生物信息学和机器学习的探索]

Shu-Qiang Huang1, Zhi-Hong Li1, Cui-Yu Tan1

  • 1Center for Reproductive Medicine, the Affiliated Qingyuan Hospital (Qingyuan People's Hospital), Guangzhou Medical University, Qingyuan, Guangdong 511518, China.

Zhonghua nan ke xue = National journal of andrology
|August 10, 2025
PubMed
概括

非阻塞性精症 (NOA) 涉及一个增强的丸免疫微环境,T细胞和巨细胞可能导致精子生成失败. 关键基因SOX30,KCTD19,ASRGL1和DRC7可以作为NOA的诊断和治疗生物标志物.

关键词:
非阻塞性精;免疫微环境;生物信息学;机器学习.

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Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
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