膝关节骨关节炎中的神经性疼痛:患病率,诊断和临床影响
Özlem Karataş1, Dilek Yapar, Aliekber Yapar
1Akdeniz Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, 07070 Kampus, Antalya, Türkiye. drozlemkaratas86@gmail.com.
Joint diseases and related surgery
|August 10, 2025
概括
神经性疼痛 (NP) 在膝关节骨关节炎 (KOA) 患者中很普遍,明显恶化疼痛和功能. 使用多种诊断工具可以提高这种常见的并发症的准确性.
科学领域:
- 整形外科 整形外科 整形外科
- 疼痛医学 医学 疼痛医学
- 神经学 神经学
背景情况:
- 膝关节关节炎 (KOA) 是慢性疼痛和残疾的主要原因.
- 神经病痛 (NP) 越来越被认为是KOA疼痛的一个组成部分.
- 了解KOA中NP的流行和影响对于有效管理至关重要.
研究的目的:
- 为了确定膝关节骨关节炎患者神经病痛的患病率.
- 评估神经病痛与KOA中的功能状态之间的关联.
- 评估不同NP选工具之间的相关性.
主要方法:
- 评估了193名患有持续膝关节疼痛的KOA患者.
- 使用 painDETECT 和 Douleur Neuropathique en 4 Questions (DN4) 问卷进行了神经病痛的评估.
- 测量疼痛严重程度 (VAS) 和功能状态 (WOMAC).
主要成果:
- 在27.5% (painDETECT) 和30.6% (DN4) 的KOA患者中发现了神经病痛.
- 患有NP的患者报告了明显更高的疼痛强度和更差的功能状态.
- 在painDETECT和DN4 (κ=0.472) 之间观察到适度的一致性.
结论:
- 神经性疼痛是膝关节骨关节炎的一个常见发现.
- 在KOA中的NP与增加的疼痛严重程度和功能障碍相关.
- 结合NP评估工具可以提高KOA的诊断准确性.
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