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高压氧气治疗对非动脉炎中心视网膜动脉阻塞 (HBOT-CRAO) 的影响

Drue M Orwig¹, Jianyong Wang², Zongyuan Li²

¹Hyperbaric and Wound Care, Division of Vascular Surgery, Corewell Health West and Michigan State University, Grand Rapids, Michigan, USA.

The American journal of emergency medicine

|August 10, 2025

概括

高压氧气疗法 (HBOT) 在完成完整治疗过程的视网膜中枢动脉封闭 (CRAO) 患者的视力显著改善. 对于在24小时内出现CRAO患者来说,HBOT是安全的,可能是可行的选择.

科学领域:

眼科医生眼科眼科
神经学神经学
高压医学的高压医学.

背景情况:

中央视网膜动脉堵塞 (CRAO) 是一种罕见的,破坏性的缺血性中风,导致严重的视力丧失.
目前对于CRAO没有指南认可的治疗方法.
有限的数据可用于CRAO的高压氧疗法 (HBOT).

研究的目的:

研究高压氧化疗 (HBOT) 对非动脉炎性中枢视网膜动脉封闭 (CRAO) 患者的潜在益处.
为了评估CRAO患者的视觉结果,这些患者接受了不同持续时间的HBOT.

主要方法:

从2019年1月到2024年12月在两个医疗中心对非动脉炎CRAO患者的回顾性研究.
患者接受全方位的HBOT (10次5天的治疗),部分的HBOT,如果在24小时治疗窗口之外,则没有HBOT.
主要结局:在出院时视觉改善 (LogMAR BCVA),使用t测试,曼-惠特尼U和奇方测试进行分析.

主要成果:

在这三个组中没有观察到显著的人口或临床差异.
完成完整HBOT疗程的患者表现出明显的视觉改善 (p=0.01).
部分或没有HBOT并没有显著改善视力;在HBOT期间发生了一次,没有其他并发症.

结论:

完整的HBOT疗程显著改善了非动脉炎CRAO患者的视觉结果.
部分或完全没有HBOT治疗没有产生可比的视觉益处.
对于CRAO患者来说,HBOT是一种安全的治疗选择,症状出现后24小时内出现.

关键词:

中央视网膜动脉封闭闭塞高压氧气疗法高压氧气疗法视力敏度视力敏度视力敏度

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