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Updated: Jun 29, 2026

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急性和慢性暴露在双和PFAS对神经元活动和网络发展的影响

Lennart V J van Melis1, Arjuna R Persad1, Anneloes M Peerdeman1

  • 1Neurotoxicology Research Group, Division of Toxicology, Institute for Risk Assessment Sciences (IRAS), Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.177, NL-3508, TD, Utrecht, the Netherlands.

The Science of the total environment
|August 10, 2025
PubMed
概括

双,但不是PFAS,在大鼠皮质培养物中显著改变了神经元活动和网络发展. 结构上的差异和暴露时间影响了双醇的神经毒性,这表明非内分泌机制.

关键词:
急性和发育性神经毒性双醇是一种双醇.内分泌干扰化合物 (EDCs) 是一种内分泌干扰化合物.微电极阵列 (MEA) 是一个微电极阵列.perfluoroalkyl 物质 (PFAS) 是一种含有高基的物质.

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