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Updated: Sep 12, 2025

Assaying Protein Kinase Activity with Radiolabeled ATP
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Published on: May 26, 2017

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双特异性线素激活蛋白质激酶激酶可以使用ADP在体外酸化MAP激酶

Pauline Juyoux1, Jill von Velsen1, Erika Pellegrini1

  • 1European Molecular Biology Laboratory, 71 avenue des Martyrs, CS 90181 F-38042 Grenoble, France.

The Journal of biological chemistry
|August 10, 2025
PubMed
概括

双特异性的MAP激酶激酶 (MAP2Ks/MEKs) 可以使用ADP或ATP激活下游的MAPK. 这一发现表明,在低ATP条件下维持细胞信号传递的机制,对于癌症等疾病的压力反应至关重要.

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