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Updated: Sep 12, 2025

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一种类型的胺酸酸激酶i5抑制YAP1信号传递

Chinmoy Ghosh1, Ruchi Kakar1, Matthew Bavuso1

  • 1Department of Oral and Craniofacial Molecular Biology, Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, Virginia, USA.

The Journal of biological chemistry
|August 10, 2025
PubMed
概括

I型胺酸酸盐酶i5 (PIPKIγi5) 通过产生PI4,5P2来抑制YES相关蛋白1 (YAP1) 信号,从而使YAP1留在细胞质中. 减少PIPKIγi5增强了YAP1的信号传递和瘤的形成.

关键词:
14-3-3 这是一个很好的时刻.PI4,5P ((2)) 的情况.在PIPKIγi5i5中使用.一个YAP1一个YAP1瘤球是指瘤球.

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