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提高甲状腺结节的特征:将TI-RADS与超声波粘度成像集成,以提高诊断准确度

Lin Wang¹, Zhidong Xuan¹, Xingyu Qian¹

¹Department Three of Ultrasound, Cangzhou Central Hospital, Cangzhou, Hebei, China.

Ultrasound in medicine & biology

|August 10, 2025

概括

超声波粘度成像,特别是S1-Vmax,结合甲状腺成像报告和数据系统 (TI-RADS) 改善了甲状腺结节恶性瘤的分化. 这种综合方法为风险分层提供了一个临床可行的工具.

科学领域:

诊断成像诊断成像的使用
甲状腺病理甲状腺病理
医学技术医学技术医学技术

背景情况:

准确区分良性和恶性甲状腺结节对于适当的患者管理至关重要.
目前的诊断工具,包括甲状腺成像报告和数据系统 (TI-RADS),在确定所有结节的特征方面存在局限性.
超声波粘度成像 (USVI) 提供了一种新的方法来评估组织特性,以提高诊断准确性.

研究的目的:

调查和验证结合TI-RADS与USVI用于区分良性和恶性甲状腺结节的临床实用性.
确定基于粘度的最佳参数,以提高诊断性能.
与单独的TI-RADS相比,评估集成的TI-RADS和USVI模型的诊断准确性.

主要方法:

一项前性诊断研究招募了437名甲状腺结节患者,分为发展 (n=306) 和验证 (n=131) 队列.
使用TI-RADS和USVI分析结节,基因病理作为参考标准.
使用接收器操作特征 (ROC) 曲线分析来确定最佳粘度参数 (S1-Vmax) 并比较诊断性能.

主要成果:

S1-Vmax在区分恶性结节方面表现强,在发育队列中曲线下的面积 (AUC) 为0.831.
结合S1-Vmax和TI-RADS的综合模型在所有分析的结节队列 (总体,大和小) 的诊断准确性上显著超过了TI-RADS单独的诊断准确性.
这些改进在独立验证队列中得到了一致的验证.

结论:

S1-Vmax是用于甲状腺结节特征的基于优越粘度的参数.
TI-RADS与USVI的整合显著提高了诊断准确度,以区分良性和恶性甲状腺结节.
这种综合方法为改善甲状腺结节风险分层提供了一个临床上有价值的工具.

关键词:

不同化的差异化这就是TI-RADS.甲状腺结节甲状腺结节超声波超声波是指超声波的使用.粘度粘度粘度是一种

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