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相关概念视频

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
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Attention-Deficit/Hyperactivity Disorder01:30

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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
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Social-emotional experiences and cultural influences play significant roles in shaping gender development. During middle childhood, from ages 6 to 11, peer groups become dominant in reinforcing gender norms. Children in this age group often align with same-gender peer groups, which actively encourage behaviors that conform to traditional gender roles. For instance, boys may be discouraged from engaging in activities perceived as feminine, reinforcing culturally dictated norms about masculinity...
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相关实验视频

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A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
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功能梯度的性别差异和ASD学龄前儿童的动态功能连接

Guangrong Wu1, Linfeng Song1, Guomin Zhang1

  • 1Department of Radiology, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, China.

CNS neuroscience & therapeutics
|August 11, 2025
PubMed
概括

自闭症谱系障碍 (ASD) 显示了幼儿大脑网络组织的性别差异. 这些发现突出了自闭症的复杂性,并为其神经成像机制提供了新的见解.

关键词:
自闭症谱系障碍 自闭症谱系障碍大脑网络 大脑网络动态功能连接的功能连接.梯度梯度是指一个梯度.机器学习模型机器学习模型一个男的男的男的男的男的男在学龄前的年龄.

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相关实验视频

Last Updated: Sep 11, 2025

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科学领域:

  • 神经科学是一个神经科学.
  • 发展心理学 发展心理学
  • 生物医学工程 生物医学工程

背景情况:

  • 自闭症谱系障碍 (ASD) 的患病率在男性中较高,但其病因不明.
  • 在ASD的学龄前儿童中,研究大脑网络组织中的性别差异至关重要.

研究的目的:

  • 为了检查ASD的学龄前男孩和女孩的多层次大脑网络重组.
  • 评估这些网络差异对临床症状的影响.
  • 探索性特异的神经成像机制在ASD.

主要方法:

  • 使用功能梯度分析和动态功能连接.
  • 在54名ASD儿童和44名典型发育 (TD) 儿童 (2-6岁) 中比较了大脑功能网络.
  • 机器学习模型评估了分类性能,以区分ASD和TD.

主要成果:

  • 自闭症组在多个大脑网络中表现出功能梯度异常.
  • 患有自闭症的男孩在注意力,边缘和默认模式网络 (DMN) 中表现出异常.
  • 患有自闭症的女孩主要在DMN中表现出初级异常,具有明显的二次和第三梯度模式.

结论:

  • 在 ASD 的学龄前儿童的功能梯度和动态功能连接方面存在显著的性别差异.
  • 这些发现强调了自闭症的异质性,并为了解其神经成像基础提供了一个新的框架.