相关实验视频
Updated: Sep 11, 2025

09:30
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
19.7K
压抑流量2D旋回回声成像,对B1不均性具有很高的耐受性,使用过度波动的断片脉冲
Jae-Youn Keum1, Jeong Hee Yoon2, Michael Garwood3
1Department of Intelligent Precision Healthcare Convergence, Sungkyunkwan University, Suwon, Republic of Korea.
Magnetic resonance in medicine
|August 11, 2025
概括
这项研究引入了高压断层 (HS) 脉冲,以改善磁共振成像 (MRI). 这种新方法有效地抑制了脑和肝脏成像中的血流器件,提高了图像质量和信号噪声比.
科学领域:
- 磁共振成像 (MRI) 是一种磁共振成像技术.
- 脉冲序列设计的设计方法
- 医学成像物理 医学成像物理
背景情况:
- 传统的旋回回声 (SE) 序列通常会受到血液流动人工物的影响.
- 现有的流量抑制方法在有效性或适用性方面可能存在局限性.
- 声平面成像 (EPI) 对运动和流动工件敏感.
研究的目的:
- 为了展示新的二维 (2D) 旋回声和旋回声扩散EPI序列.
- 为了利用超标断层 (HS) 脉冲进行 π/2 激发和 π 重定焦.
- 为了评估HS脉冲在MRI中抑制流动工件的有效性.
主要方法:
- 开发了一个理论框架,用于 HS 脉冲的移动旋转的相分散.
- 执行数值模拟以验证理论分析.
- 在3T扫描仪上使用幻影,人脑和肝脏成像实现并测试了序列.
主要成果:
- 提出的HS脉冲序列显著减少了大脑和肝脏图像中的血流器件.
- 静脉血流抑制在大脑中优于传统的SE与先和.
- 肝脏成像显示,由于B1耐受性改善,明亮血液信号减少,信号与噪声比提高 (10-30%).
结论:
- 在2D SE和SE扩散EPI中用HS脉冲取代sinc脉冲,可以实现有效的流量抑制.
- 该方法提供了部分B1不敏感性,增强了强度.
- 这种技术对于要求减少血管信号污染的应用具有前景,例如肝脏和大脑成像.
相关概念视频
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
917
A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
917
Double Resonance Techniques: Overview
293
Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
Spin decoupling is usually achieved by...
293
¹H NMR: Interpreting Distorted and Overlapping Signals
1.1K
Spin systems where the difference in chemical shifts of the coupled nuclei is greater than ten times J are called first-order spin systems. These nuclei are weakly coupled, and their chemical shifts and coupling constant can generally be estimated from the well-separated signals in the spectrum.
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are...
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are...
1.1K
NMR Spectrometers: Resolution and Error Correction
775
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
775
Magnetic Resonance Imaging
6.9K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
6.9K
NMR Spectroscopy: Spin–Spin Coupling
1.6K
The spin state of an NMR-active nucleus can have a slight effect on its immediate electronic environment. This effect propagates through the intervening bonds and affects the electronic environments of NMR-active nuclei up to three bonds away; occasionally, even farther. This phenomenon is called spin–spin coupling or J-coupling. Coupling interactions are mutual and result in small changes in the absorption frequencies of both nuclei involved. While nuclei of the same element are involved...
1.6K

