概括
对注意力缺陷/多动障碍 (ADHD) 的兴奋剂治疗可能与精神病有关,发病率为0.1-1.2%. 需要进一步的研究来澄清风险,并指导精神病发作后的治疗决策.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 注意缺陷/多动障碍 (ADHD) 治疗通常涉及刺激剂以纠正多巴胺低活性.
- 多巴胺失调也与精神病和精神分裂症有关,这些精神病的特征是过度活跃.
研究的目的:
- 研究兴奋剂药物对ADHD成年人精神病发展的潜在风险调节效应.
- 审查有关多动症治疗期间精神病发病率和管理的现有文献.
主要方法:
- 在PubMed,科学网和科克兰图书馆的系统文献搜索.
- 包括五项系统性审查,检查ADHD患者的兴奋剂使用和精神病.
主要成果:
- 在ADHD的兴奋剂治疗期间,精神病的发病率估计在0.1%至1.2%之间.
- 目前的证据不足以确定治疗性兴奋剂剂量是否会增加精神病风险.
- 有有限的证据支持在精神病发作后长时间停止兴奋剂治疗.
结论:
- 对于ADHD的兴奋剂治疗和精神病风险之间的关系需要进一步调查.
- 在兴奋剂治疗期间发展精神病的ADHD患者管理的临床指南需要更强有力的证据.
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