电子烟使用对老年前吸烟者的心血管风险标志物的影响:系统性审查和元分析
Anil Reddy Padi1, Rutvij Patel2, Maheshwar Dumpala1
1Internal Medicine, Osmania Medical College, Hyderabad, IND.
电子烟使用与心血管风险有关,如动脉硬和氧化应激,尽管比传统吸烟少. 需要对长期影响进行更多的研究,特别是对双重使用者的长期影响.
科学领域:
- 心血管科学 心血管科学
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 与传统吸烟相比,电子烟 (EC) 的使用在心血管安全性方面存在争议.
- 使用EC与动脉硬,内皮功能障碍和氧化应激有关.
研究的目的:
- 系统地审查和元分析EC吸烟与非吸烟和传统吸烟之间的心血管风险.
主要方法:
- 搜索范围包括Scopus,PubMed,科学网,谷歌学者 (2015-2025年).
- 包括横截面,RCT和队列研究.
- 执行随机效应模型元分析,评估I2统计数据的异质性,漏斗图和埃格尔测试.
主要成果:
- 与非吸烟者相比,EC吸烟者显示血管硬和氧化应激增加.
- 来自EC的心血管风险低于传统香烟的风险.
- 在EC吸烟和心血管风险之间发现了中等积极的关系 (r = 0.60).
结论:
- 虽然EC吸烟带来心血管风险,但不如传统吸烟那么严重.
- 实质性的异质性 (I2 = 99.99%) 需要进一步研究.
- 长期的心血管影响,特别是双重使用者,需要专门的研究.
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