相关实验视频

Updated: Sep 11, 2025

Voltage-Dependent Potassium Current Recording on H9c2 Cardiomyocytes via the Whole-Cell Patch-Clamp Technique
08:11

Voltage-Dependent Potassium Current Recording on H9c2 Cardiomyocytes via the Whole-Cell Patch-Clamp Technique

Published on: November 11, 2022

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一系列电压协议设计用于快速捕获hERG动力学

Chon Lok Lei1,2, Dominic J Whittaker3, Monique J Windley4,5

  • 1University of Macau Institute of Translational Medicine, Taipa, Macao.

Wellcome open research
|August 11, 2025
PubMed
概括

我们开发了简单的电压协议,以有效地研究人类以太基因相关基因 (hERG) 离子通道门. 这些方法有助于完善hERG通道行为的数学模型.

关键词:
计算模型是一种计算模型.实验设计 实验设计离子通道 离子通道 离子通道数学模型是一个数学模型.补丁紧固件 补丁紧固件

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Recapitulation of an Ion Channel IV Curve Using Frequency Components10:14

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相关概念视频

Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
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