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Updated: Sep 11, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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在药物开发和食植物化学品中应用生理学基础的药理动力学 (PBPK) 模型

PoChung Chou1,2, Ahmad Shannar1,2, Yuxin Pan1,2

  • 1Graduate Program in Pharmaceutical Science, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 USA.

Current pharmacology reports
|August 11, 2025
PubMed
概括

基于生理学的药理动力学 (PBPK) 建模通过预测药物行为和相互作用来增强药物开发. 这种强大的工具还有助于了解饮食中的植物化学物质,提高效率和安全.

关键词:
饮食中的植物化学物质药物相互作用 药物相互作用扩展到特殊人口.配方模拟的模拟方法领先优化和候选人评估.PBPKK PBPK 的意思是什么意思

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