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RAG复合酶表达区分自然杀手细胞的发展

Jasmin Sprissler1,2, Ulrich Pannicke3, Eva-Maria Rump3

  • 1Department of Pediatrics and Adolescent Medicine, University Ulm Medical Center, Ulm, Germany.

Frontiers in immunology
|August 11, 2025
PubMed
概括

重组激活基因 (RAG) 表达影响自然杀手 (NK) 细胞的发展,导致特定的遗传重组并影响它们的功能. 这表明RAG在NK细胞成熟和效应器功能中的新角色.

关键词:
对DNA损伤的反应反应在NK细胞分化过程中,NK细胞分化.在RAG-fate记者.有关RNA测序的RNA测序V(D) J的重组组合.诱导多能干细胞的诱导干细胞.淋巴细胞的原始细胞.

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