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Updated: Sep 11, 2025

A Seminiferous Tubule Squash Technique for the Cytological Analysis of Spermatogenesis Using the Mouse Model
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[NSD1调节H3K36me2在非阻塞性亚精子症的发病过程中]

Xuan Zhuang1,2, Zhen-Xin Cai1, Yu-Feng Yang2

  • 1Department of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian 350122, China.

Zhonghua nan ke xue = National journal of andrology
|August 11, 2025
PubMed
概括

核受体结合的SET-域蛋白1 (NSD1) 和H3K36me2水平在非阻塞性亚精 (NOA) 丸中降低. 下调的NSD1通过影响KIT,SPO11和ACRV1.1等关键基因来破坏精子生成.

关键词:
非阻塞性亚精;精子发生;核受体结合SET域蛋白1;H3K36me2;男性不孕不育.

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