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Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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结合葡萄皮质皮质激素与免疫检查点抑制剂对淋巴细胞激活基因-3和编程死亡-1表达的缓解作用

Smadar Gertel1,2, Ari Polachek2,3, Victoria Furer1,2

  • 1Department of Rheumatology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.

European journal of immunology
|August 11, 2025
PubMed
概括

结合癌症免疫疗法 (ICI) 的葡萄糖皮质类药物可能会通过增加淋巴细胞激活基因-3 (LAG-3) 表达细胞来干扰治疗. 这种组合疗法还改变了细胞因子的产生和T细胞的增殖.

关键词:
免疫检查点抑制剂 免疫检查点抑制剂现场行动小组-3在T细胞,T细胞.葡萄糖皮质类药物是什么结合细胞单细胞 (synovial monocytes) 是一种细胞.

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