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在多创伤患者中的晶体液与体液复苏:系统性审查
Julia Dormann1, Karolina Dahms1, Eva Steinfeld1
1Department of Intensive Care Medicine and Intermediate Care, Medical Faculty, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.
概括
对于多创伤患者来说,结晶液复苏与合液复苏相比,死亡率没有显著差异. 这一发现是基于当前关于重症监护机构流体治疗的证据.
科学领域:
- 关键护理医学 关键护理医学
- 创伤外科 手术 创伤外科
- 液体复苏 复苏 液体复苏 复苏
背景情况:
- 多创伤患者需要及时进行液体复苏.
- 在晶体溶液和体溶液之间做出选择是一个关键的临床决定.
- 在多创伤中比较这些流体类型的证据正在发展.
研究的目的:
- 在多创伤患者中,系统地比较晶体液与体液复苏的治疗结果.
- 评估液体类型对该患者群体死亡率的影响.
主要方法:
- 随机对照试验 (RCT) 的系统审查和系统审查.
- 在2022年8月之前搜索了主要数据库 (PubMed,Cochrane,Web of Science)
- 包括的研究集中在重症监护室 (ICU) 的多创伤患者身上.
主要成果:
- 包括一个涉及2857名成年参与者的RCT.
- 在结晶体和合体之间没有观察到28天死亡率的显著差异.
- 对死亡结果的证据质量被评为非常低.
结论:
- 与成人多创伤患者的体体积疗法相比,晶体体体积疗法在死亡率上没有显著差异.
- 需要进一步进行高质量的研究,才能确定最佳流体策略.
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