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在心脏瘤模型中,对免疫检查点抑制剂治疗的最佳控制

Solveig A van der Vegt1, Ruth E Baker1, Sarah L Waters2

  • 1Mathematical Institute, University of Oxford, Oxford, UK.

Bulletin of mathematical biology
|August 11, 2025
PubMed
概括

癌症治疗的数学模型现在包括自身免疫性心肌炎,免疫检查点抑制剂 (ICI) 的致命副作用. 这种方法通过平衡治疗益处与心脏风险来优化ICI剂量计划.

关键词:
自免疫性心肌炎的发生.免疫检查点抑制剂 免疫检查点抑制剂最佳的控制控制是最好的控制.瘤的生长 瘤的生长

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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