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关于肉瘤中铁亡的知识映射:一个圣经识别和生物信息学分析 (2012-2023)

Zhen Cao¹, Chanjuan Qu¹, Fan Yang¹

¹Department of Radiology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, People's Republic of China.

Discover oncology

|August 11, 2025

概括

对细胞死亡过程铁亡的研究正在不断发展,用于治疗肉瘤. 一个关键的基因,ACSF2,显示出作为肉瘤患者的预后生物标志物有前途,需要进一步调查.

科学领域:

在瘤学瘤学.
生物医学科学生物医学科学
遗传学是一个遗传学.

背景情况:

肉瘤是一种罕见的中介质组织癌症,会给诊断和治疗带来挑战.
铁,一种独特的依赖铁的细胞死亡,正在成为对抗肉瘤的治疗策略.
了解铁亡对于改善肉瘤治疗和克服药物耐药性至关重要.

研究的目的:

用 библиометри和生物信息学方法分析肉瘤中铁亡的研究格局.
确定主要趋势,有影响力的研究小组,以及肉瘤和铁亡研究中的新兴话题.
探索与铁亡相关的基因作为肉瘤中的生物标志物的潜力.

主要方法:

从CiteSpace,VOSviewer和R包"bibliometrix"使用的科学网络核心集合中对出版物 (2012-2023) 的图书统计分析.
使用R Studio和公共数据库进行生物信息学分析,以识别与铁死相关的基因.
文献搜索侧重于铁亡和肉瘤.

主要成果:

观察到对铁亡和肉瘤的研究持续增加,全球合作.
确定了主要的作者,机构,研究集群和趋势.
已证实与铁死相关的基因ACSF2在各种类肉瘤中具有显著作用,具有潜在的预后价值.

结论:

图书统计和生物信息学分析为肉瘤和铁亡研究提供了宝贵的见解.
未来的研究应该专注于铁灭机制,包括免疫微环境和临床应用.
ACSF2是肉瘤的潜在预后生物标志物,需要进一步验证.

关键词:

图书统计学图书统计学生物信息学是一种生物信息学.铁化是铁化的一种.肉瘤肉瘤是一种肉瘤.瘤这些瘤

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