直肠癌的多维分析:存活率分析及其多变量趋势 - 单一机构宏观研究II
Shaqul Qamar Wani1, Talib Khan2, Saiful Yamin Wani3
1Department of Radiation Oncology, State Cancer Institute, Srinagar, Jammu and Kashmir, India.
Indian journal of cancer
|August 11, 2025
概括
结直肠癌的存活率受到疾病阶段,治疗和婚姻状况的影响. 早期检测和及时,适当的治疗是改善直肠癌患者治疗结果的关键.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 临床研究 临床研究
背景情况:
- 结直肠癌是一个重大的全球健康挑战.
- 了解预后因素对于改善患者存活率至关重要.
研究的目的:
- 分析直肠癌患者的整体存活率 (OS) 和无病存活率 (DFS).
- 调查临床人口统计因素与生存结果之间的关系.
主要方法:
- 在一所大学教学医院进行了一项宏观研究.
- 收集了2014-2016年的数据,并跟踪患者直到2021年6月.
- 与吸烟,婚姻状况,疾病阶段,CRM和治疗相关的OS和DFS被评估.
主要成果:
- 五年平均DFS和OS分别为59.13和56.81个月.
- 第一个阶段的直肠癌显示出明显更好的生存率 (83.96个月DFS,84.16个月OS) 与第四阶段 (27.72个月DFS,32.61个月OS) 相比.
- 前置手术 (59.93个月的DFS,62.70个月的OS) 和CRM负状态 (62.91个月的DFS,OS好处) 与生存率的改善有关. 已婚患者也显示出统计学上显著的生存益处.
结论:
- 疾病阶段,周围切除边缘 (CRM) 状态,前期手术和婚姻状况显著影响直肠癌的OS和DFS.
- 早期检测和及时,适当的治疗对于提高直肠癌患者的生存模式至关重要.
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