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肠道微生物群作为一种代谢媒介,可以预防或减轻MASLD

Jing Luo¹, Yijiang Wei¹, Zhexin Fan^1,2,3,4

¹School of Food Science and Technology, Shihezi University, Shihezi, China.

Critical reviews in food science and nutrition

|August 11, 2025

概括

饮食调整可以重塑肠道微生物组,以预防与代谢功能障碍相关的脂肪性肝病 (MASLD). 了解肠道微生物群的理解

科学领域:

微生物学微生物学
代谢障碍代谢障碍代谢障碍
营养科学营养科学

背景情况:

与代谢功能障碍相关的脂肪性肝病 (MASLD) 是一种普遍的代谢障碍.
肠道微生物组在宿主健康和代谢活动中起着至关重要的作用.
肠肝轴介导肠道微生物群和肝功能之间的通信.

研究的目的:

审查肠道微生物群和MASLD之间的复杂关系.
突出肠道微生物组成和新陈代谢对MASLD的影响.
澄清饮食成分对MASLD进展和预防的影响.

主要方法:

关于肠道微生物群,新陈代谢和MASLD的综合文献综述.
微生物代谢物的分析及其对肝脏过程的影响.
探索调节肠道微生物群的饮食干预措施.

主要成果:

肠道微生物群的组成和新陈代谢显著影响MASLD.
饮食成分调节肠道微生物群和肠道环境.
针对性调节肠道微生物群是MASLD的潜在治疗策略.

结论:

战略性饮食调整可以重塑肠道微生物组,以防止MASLD.
针对肠道微生物群的精确营养干预措施需要进一步探索.
了解肠肝轴对于管理MASLD至关重要.

关键词:

我们的肠道微生物群.饮食饮食饮食饮食肠道微生物代谢物的代谢物.肠 - 肝轴肠 - 肝轴与代谢功能障碍相关的肥胖症肝脏疾病.非酒精性脂肪性肝病是什么?

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